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Top 25 Genetically Engineered Novels on Royal Road (2026)

Updated November 2026 · ranked by average reader rating

Genetically Engineered Novels are among the most popular stories on Royal Road.

This guide ranks the best by average reader rating. The current top picks are Seeking Strays, Lost and Found (Warhammer 40k SI) and Myth//OS. Some of them are already finished, so you can binge without waiting for updates.

The 25 best Genetically Engineered novels on Royal Road

  1. Seeking Strays

    4.89 · 82 chapters · Ongoing

    Protect my sister. That’s all that ever mattered to me. Come hell or high water, I’d do anything if it meant my sweet little sister could have just one more day of a peaceful life. Anything. There was just one issue—I was burning the…

  2. Lost and Found (Warhammer 40k SI)

    4.81 · 110 chapters · Ongoing

    Lost and Found: Living as a Relic of Ages Past. Aboard a Grand Cruiser once lost now owned by a Rogue Trader dynasty with a heavy Adeptus Mechanicus presence. A soul wakes up shortly after the formation of the Cicatrix Maledictum, in a…

  3. Myth//OS

    4.81 · 71 chapters · Hiatus
    ⏸ On hiatus · No new chapter since Jun 18, 2026 (5 months ago).

    What’s left when it all falls apart? Where do I go when the path forward is blocked? How do people just move on like nothing ever happened? A change in location certainly helped me. Bastion, the last hope of civilization. It's bright…

  4. The Perfect Run

    4.80 · 131 chapters · Completed

    The Perfect Run is now available on Amazon and Audible: Volume 1 (Audiobook), Volume 2 (Audiobook), Volume 3 Ryan "Quicksave" Romano is an eccentric adventurer with a strange power: he can create a save-point in time and redo his life…

  5. Re:Cursed

    4.75 · 260 chapters · Ongoing

    As the perfect sacrifice, it is only natural that Nix be sacrificed to the ancient gods lurking in the depths of the black hole. But she didn’t die. Finding herself seven years in the past — to the day of her first cursed mutation — Nix…

  6. The Call of the Hollow Men

    4.75 · 25 chapters · Completed

    An experimental AI that he doesn’t remember stealing, thrown an unknown number of years into the future and promptly enslaved, Mat decides that everything sucks, and people still do mean things to one another. But alien life has been…

  7. Systema Delenda Est

    4.74 · 72 chapters · Completed

    Get it on Amazon Book One: Invading The System When the System came to Earth, technology failed, monsters appeared, and billions died as humans were inducted into the game-like physics the System enforced. Unfortunately for the System…

  8. Teddy Bears on Brigade [A SCS Fanfiction]

    4.73 · 465 chapters · Ongoing

    Chapters released Mon/Wed/Fri. Evelyn "Teddy" Claire is a street kid just trying to make ends meet. That's hard to do when you live in the undercity, a near slum found underneath the foundations of the megacity of Calgary. Usually, her…

  9. The Exorcist Doctor [Stubbing January 19th]

    4.72 · 208 chapters · Ongoing

    They say death is a curse that cannot be treated by any priest, saint, or doctor in the City of Plagues. Gael Halloway would beg to differ. Gael is a brilliant but unlicensed doctor practicing medicine in the slums of the lower city, and…

  10. Battle Trucker

    4.71 · 20 chapters

    The first book of Battle Trucker, What the Truck, is now available on Kindle Unlimited, Amazon, and as an Audiobook narrated by the fantastic Zura Johnson! A preview of book 1 (10%) is posted here, as is the in-progress book 2. Thanks for…

  11. The Rings of Jupiter [A Dark Cyberpunk LitRPG] (STUBBED)

    4.71 · 69 chapters

    BOOK 1 IS OUT ON AMAZON! --- Raziel is meant to be dead. He shouldn't have levels, skills, or a metal arm that throws lightning. But he does, and he's only just getting started. Once a legendary Gunslinger of the Outer Ring, Raziel has…

  12. CyberGene [Volume 1 Complete! 500k+ Words] [LitRPG w/ cybernetics + mutations]

    4.66 · 258 chapters · Hiatus
    ⏸ On hiatus · No new chapter since Aug 13, 2026 (3 months ago).

    Chapters M-W-F 9AM. Volume 1 Blood and Steel: All Three Acts Complete! Volume 2 Thunder and Webs: Act Two Ongoing! Discord - Patreon - Spotify Playlist Upgrade. Consume. Evolve. Whether it’s cybernetics or mutations, this world demands…

  13. Godclads

    4.65 · 530 chapters

    Professionally edited and published versions of volumes 1 and 2 can be found on Kindle and as audiobooks on Audible! Avo was born to destroy New Vultun. In a twist of fate, he’ll become its only hope for salvation. The gods were the…

  14. A Journey in Darkness

    4.64 · 88 chapters

    A Journey in Darkness is the story of a human girl who finds herself displaced far, far away from home, in a new world filled with wonders to discover and perils to overcome in her very own way. Waking up in a cave in her pajamas will…

  15. A Spark of Sylvan Flame

    4.61 · 117 chapters · Hiatus
    ⏸ On hiatus · No new chapter since Jul 2, 2026 (4 months ago).

    No one cares about the wastes. These are the words Spark has heard all life long. The masters of the world, despite dining on the 'natural foods' produced by Spark's people, would rather let them bleed than provide military support. Even…

  16. Fleabag: A Monster Evolution LitRPG

    4.61 · 87 chapters · Hiatus
    ⏸ On hiatus · the author says: “So- insert thanos meme where he says "fine, i'll do it myself" (The 'HIATUS' tag is auto-applied by RR after a month of no updates.”

    In the deepest reaches of the Bone Pits, a canine seemingly like any other woke up in the ruined remains of a wooden box. With knowledge it shouldn't have, fleeting memories it couldn't reach, and the icy grasp of death crawling up its…

  17. Magical Girl Platinum

    4.60 · 78 chapters · Completed

    Humanity stands on the brink of destruction. Mutating creatures are attacking. The planetary colonies sit in disrepair, and the fae control magic; the one thing humanity needs to stop their demise. Inheriting magic should have been…

  18. Tiny Dungeon Core [Books 1 & 2 STUBBed for Publication]

    4.59 · 38 chapters

    In a world of Dungeons and High Spirits, when the Archmage Calamvor dies, creating an artificial Dungeon Core, he sets off a series of events that even the godly High Spirits couldn’t have predicted. His creation, stolen from him by the…

  19. Tarnished Honor

    4.57 · 108 chapters · Completed

    What would you consider a bad day? Having your father threaten the family shrine in order to get you to cooperate? Maybe having aliens invade? Well Reina experienced both. On the same day. So when the sky is ripped open, and aliens rain…

  20. The Discarded, Half-Eaten Apple Core New Life. An OP Dungeon Post-Apocalyptic LitRPG.

    by MDW
    4.55 · 88 chapters

    [A failed Participant in the January 2023 Community Contest: I forgot to fill the form] The world ended. Bam! The Apocalypse opened the gates of Hell, demons killed everyone. Including me. But I got a second chance of life. Though it was…

  21. The Factory Must Grow - [Book 3: The Wheels Must Turn]

    4.54 · 131 chapters · Ongoing

    Constructing a portal is a monumental undertaking, yet the Forerunners have guided dozens of civilizations to that end and know exactly what is needed. Thousands of laborers to source and process materials. Hundreds of brilliant artisans…

  22. Demonic Devourer

    4.53 · 2 chapters

    Series complete on Kindle Devour. Level up. Repeat. Awakening in an abandoned lab with no knowledge of the world, Evelyn is empowered by a system that grants her bloody magical powers in exchange for finishing missions and consuming her…

  23. Deus in Machina (a Warhammer 40K-setting inspired LitRPG)

    by Tony
    4.53 · 375 chapters · Ongoing

    In a galaxy forsaken, infernal gateways tear asunder, unleashing Hell’s legions to crush all in their grasp. From the ashes, Theosis, the Divine System and God’s voice in this temporal realm, ascends. It forges a grand Empire, waging four…

  24. Shaper of Metal Post-Apoc Progression LitRPG

    4.51 · 47 chapters

    Amazon, Kindle Unlimited, & Audible available HERE! Monsters overrun Earth like a plague, and System powers for a chosen few aren't enough to take it back. Humanity needs more. As a former military transport pilot, Jack Laker once met the…

  25. Evolution Re:start

    4.49 · 49 chapters

    An alien virus changes things on earth for good. William is given a second chance at life, to go 15 years into the past in order to stop humanity from completely falling apart. If failing that, he at least wants enough power to protect…

More Genetically Engineered novels to explore

Want everything in one place? Browse all Genetically Engineered stories.

Frequently asked questions

What is the best Genetically Engineered novel on Royal Road?

Right now Seeking Strays by Lost Rain is the highest rated, with an average rating of 4.89 out of 5 and 82 chapters. Lost and Found (Warhammer 40k SI) by Latscryjml comes next.

How are these stories ranked?

Stories are ordered by their average reader rating on Royal Road, and the guide is refreshed as ratings change.

Are there completed Genetically Engineered novels I can binge?

Yes, including The Perfect Run, The Call of the Hollow Men and Systema Delenda Est.

Where can I read these Genetically Engineered novels?

Every story is free to read on Royal Road. Open a story's page and use the Read button to go straight to it. FicGems doesn't host any chapters.

Related top lists

Genetically Engineered Novels